Using the C.WASH™ to conduct automated, non-contact bead-based DNA purification

Discover how C.WASH™ automates bead-based DNA purification, reducing contamination and pipette tip use in scRNA-seq workflows for greater efficiency.

About the App Note

Magnetic bead cleanup is a manual bottleneck in scRNA-seq workflows, often increasing time and tip consumption. The C.WASH automates this step: it uses centrifugal force to gently remove liquids while retaining magnetic beads, then dispenses wash reagents non-contact, reducing cross-contamination.

In a test with alternating human and mouse cells in 384-well plates, C.WASH showed no cross-species contamination and reduced pipette tip use dramatically.

Learn more about how:

  • The C.WASH performs fully automated, non-contact bead-based cleanup
  • Cross-sample contamination is avoided, even in alternating human/mouse wells
  • Tip consumption is cut significantly in high-throughput scRNA-seq workflows

 

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